Genetics of the faint-hearted: great results, alternate hypothesis.

نویسندگان

  • Andrew D Krahn
  • Brenda Gerull
  • Robert S Sheldon
چکیده

In this issue of Circulation: Cardiovascular Genetics, Barsheshet et al shed novel and unexpected light on the genetics of syncope, defined as a transient loss of consciousness caused by cerebral hypoperfusion with spontaneous recovery. Syncope is very common, with a cumulative incidence of 37% by age 60 years.1,2 In “young” patients, by far the most common cause of syncope is vasovagal syncope, with a well-characterized symptom complex and a benign natural history.3,4 Hidden in the forest of vasovagal syncope are rare but more worrisome sentinel events that reflect more life-threatening arrhythmic disorders, particularly inherited arrhythmia syndromes such as long-QT syndrome (LQTS).5 The genetics of these syndromes are now relatively clear.

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Editorial Genetics of the Faint - Hearted Great Results , Alternate Hypothesis

In this issue of Circulation: Cardiovascular Genetics, Barsheshet et al shed novel and unexpected light on the genetics of syncope, defined as a transient loss of consciousness caused by cerebral hypoperfusion with spontaneous recovery. Syncope is very common, with a cumulative incidence of 37% by age 60 years.1,2 In “young” patients, by far the most common cause of syncope is vasovagal syncope...

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عنوان ژورنال:
  • Circulation. Cardiovascular genetics

دوره 4 5  شماره 

صفحات  -

تاریخ انتشار 2011